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Deep Amino Acid Sequencing of Native Brain GABA(A) Receptors Using High-Resolution Mass Spectrometry
Mass spectrometric sequencing of low abundance, integral membrane proteins, particularly the transmembrane domains, presents challenges that span the multiple phases of sample preparation including solubilization, purification, enzymatic digestion, peptide extraction, and chromatographic separation....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3270104/ https://ncbi.nlm.nih.gov/pubmed/22338125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.011445 |
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