Direct Monitoring of Protein O-GlcNAcylation by High-Resolution Native Mass Spectrometry

[Image: see text] O-GlcNAcylation is one of the most abundant metazoan nuclear-cytoplasmic post-translational modifications. Proteins modified by O-GlcNAc play key cellular roles in signaling, transcription, metabolism, and cell division. Mechanistic studies on protein O-GlcNAcylation are hampered b...

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Bibliographic Details
Published in:ACS Chem Biol
Main Authors: Leney, Aneika C., Rafie, Karim, van Aalten, Daan M. F., Heck, Albert J. R.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2017
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565903/
https://ncbi.nlm.nih.gov/pubmed/28609614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00371
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