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An Alternative Signal 3: CD8(+) T Cell Memory independent of IL-12 and Type I IFN is dependent on CD27/OX40 signaling
Type I IFN and IL-12 are well documented to serve as so called “signal 3” cytokines, capable of facilitating CD8+ T cell proliferation, effector function and memory formation. While their ability to serve in this capacity is well established, to date, no non-cytokine signal 3 mediators have been cle...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269501/ https://ncbi.nlm.nih.gov/pubmed/22178730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.12.017 |
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