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Type I Interferon-dependent T cell activation is mediated by IFN-dependent DC OX40L expression and independent of T cell IFNR expression

Type-I-interferons are important for direct control of viral infection and for generation of adaptive immune responses. Recently, direct stimulation of CD4+ T cells via type-I-interferon receptor has been shown to be necessary for the formation of function CD4+ T cell responses. In contrast, we find...

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Detalhes bibliográficos
Main Authors: Kurche, Jonathan S., Haluszczak, Catherine, McWilliams, Jennifer A., Sanchez, Phillip J., Kedl, Ross M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253193/
https://ncbi.nlm.nih.gov/pubmed/22156349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102550
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