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An Alternative Signal 3: CD8(+) T Cell Memory independent of IL-12 and Type I IFN is dependent on CD27/OX40 signaling

Type I IFN and IL-12 are well documented to serve as so called “signal 3” cytokines, capable of facilitating CD8+ T cell proliferation, effector function and memory formation. While their ability to serve in this capacity is well established, to date, no non-cytokine signal 3 mediators have been cle...

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Detalhes bibliográficos
Main Authors: Sanchez, Phillip J., Kedl, Ross M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269501/
https://ncbi.nlm.nih.gov/pubmed/22178730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.12.017
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