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Activation of OX40 and CD27 Costimulatory Signalling in Sheep through Recombinant Ovine Ligands

Members of the tumour necrosis factor (TNF) superfamily OX40L and CD70 and their receptors are costimulating signalling axes critical for adequate T cell activation in humans and mice but characterisation of these molecules in other species including ruminants is lacking. Here we cloned and expresse...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Rojas, José Manuel, Alejo, Alí, Avia, Jose Miguel, Rodríguez-Martín, Daniel, Sánchez, Carolina, Alcamí, Antonio, Sevilla, Noemí, Martín, Verónica
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350415/
https://ncbi.nlm.nih.gov/pubmed/32580486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8020333
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