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IFNγ production by memory helper T cells is required for CD40-independent alloantibody responses
Cognate T/B cell interactions and CD40/CD154 costimulation are essential for productive humoral immunity against T-dependent antigens. We reported that memory CD4 T cells can deliver help to B cells and induce pathogenic IgG alloantibodies (alloAb) in the absence of CD40/CD154 interactions. To deter...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4297685/ https://ncbi.nlm.nih.gov/pubmed/25548230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401573 |
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