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A human cell-based reporter detects microhomology-mediated end joining
DNA double-strand breaks (DSBs) are most often repaired by two pathways in mammalian cells, homologous recombination or non-homologous end joining. Biochemical and genetic studies showed that DSBs can also be joined via microhomology-mediated end joining (MHEJ), which is always mutagenic and may res...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268871/ https://ncbi.nlm.nih.gov/pubmed/22197482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2011.12.003 |
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