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Estimating Allele Frequency from Next-Generation Sequencing of Pooled Mitochondrial DNA Samples

Background: Both common and rare mitochondrial DNA (mtDNA) variants may contribute to genetic susceptibility to some complex human diseases. Understanding of the role of mtDNA variants will provide valuable insights into the etiology of these diseases. However, to date, there have not been any large...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Tao, Pradhan, Kith, Ye, Kenny, Wong, Lee-Jun, Rohan, Thomas E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Research Foundation 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268604/
https://ncbi.nlm.nih.gov/pubmed/22303347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2011.00051
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