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Estimating Allele Frequency from Next-Generation Sequencing of Pooled Mitochondrial DNA Samples
Background: Both common and rare mitochondrial DNA (mtDNA) variants may contribute to genetic susceptibility to some complex human diseases. Understanding of the role of mtDNA variants will provide valuable insights into the etiology of these diseases. However, to date, there have not been any large...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Research Foundation
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268604/ https://ncbi.nlm.nih.gov/pubmed/22303347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2011.00051 |
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