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PoolHap: Inferring Haplotype Frequencies from Pooled Samples by Next Generation Sequencing

With the advance of next-generation sequencing (NGS) technologies, increasingly ambitious applications are becoming feasible. A particularly powerful one is the sequencing of polymorphic, pooled samples. The pool can be naturally occurring, as in the case of multiple pathogen strains in a blood samp...

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Autors principals: Long, Quan, Jeffares, Daniel C., Zhang, Qingrun, Ye, Kai, Nizhynska, Viktoria, Ning, Zemin, Tyler-Smith, Chris, Nordborg, Magnus
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016441/
https://ncbi.nlm.nih.gov/pubmed/21264334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015292
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