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Estimation of allele frequency and association mapping using next-generation sequencing data
BACKGROUND: Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing, a cost effective approach is to use medium or low-coverage data (e.g., < 15X). However, SNP calling and allele frequ...
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| Главные авторы: | , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3212839/ https://ncbi.nlm.nih.gov/pubmed/21663684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-231 |
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