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Estimation of allele frequency and association mapping using next-generation sequencing data
BACKGROUND: Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing, a cost effective approach is to use medium or low-coverage data (e.g., < 15X). However, SNP calling and allele frequ...
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| Hlavní autoři: | , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3212839/ https://ncbi.nlm.nih.gov/pubmed/21663684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-231 |
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