Estimation of allele frequency and association mapping using next-generation sequencing data

BACKGROUND: Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing, a cost effective approach is to use medium or low-coverage data (e.g., < 15X). However, SNP calling and allele frequ...

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Detalhes bibliográficos
Main Authors: Kim, Su Yeon, Lohmueller, Kirk E, Albrechtsen, Anders, Li, Yingrui, Korneliussen, Thorfinn, Tian, Geng, Grarup, Niels, Jiang, Tao, Andersen, Gitte, Witte, Daniel, Jorgensen, Torben, Hansen, Torben, Pedersen, Oluf, Wang, Jun, Nielsen, Rasmus
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212839/
https://ncbi.nlm.nih.gov/pubmed/21663684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-231
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