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A Bayesian Multilocus Association Method: Allowing for Higher-Order Interaction in Association Studies

For most common diseases with heritable components, not a single or a few single-nucleotide polymorphisms (SNPs) explain most of the variance for these disorders. Instead, much of the variance may be caused by interactions (epistasis) among multiple SNPs or interactions with environmental conditions...

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Detalhes bibliográficos
Main Authors: Albrechtsen, Anders, Castella, Sofie, Andersen, Gitte, Hansen, Torben, Pedersen, Oluf, Nielsen, Rasmus
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894584/
https://ncbi.nlm.nih.gov/pubmed/17435250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.071696
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