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Ionic Residues of Human Serum Transferrin Affect Binding to the Transferrin Receptor and Iron Release
Efficient delivery of iron is critically dependent on the binding of diferric human serum transferrin (hTF) to its specific receptor (TFR) on the surface of actively dividing cells. Internalization of the complex into an endosome precedes iron removal. The return of hTF to the blood to continue the...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3267578/ https://ncbi.nlm.nih.gov/pubmed/22191507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201661g |
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