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Inequivalent Contribution of the Five Tryptophan Residues in the C-lobe of Human Serum Transferrin to the Fluorescence Increase when Iron is Released
Human serum transferrin (hTF), with two Fe(3+) binding lobes transports iron into cells. Diferric hTF preferentially binds to a specific receptor (TFR) on the surface of cells and the complex undergoes clathrin dependent receptor-mediated endocytosis. The clathrin-coated vesicle fuses with an endoso...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2664620/ https://ncbi.nlm.nih.gov/pubmed/19281173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8022834 |
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