Oncogenic β-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in mice

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Its pathogenesis is frequently linked to liver inflammation. Gain-of-function mutations in the gene encoding β-catenin are frequent genetic modifications found in human HCCs. Thus, we investigated whether in...

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Hlavní autoři: Anson, Marie, Crain-Denoyelle, Anne-Marie, Baud, Véronique, Chereau, Fanny, Gougelet, Angélique, Terris, Benoit, Yamagoe, Satoshi, Colnot, Sabine, Viguier, Mireille, Perret, Christine, Couty, Jean-Pierre
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266772/
https://ncbi.nlm.nih.gov/pubmed/22251704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43937
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