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Structure-Activity Relationships of Truncated C2- or C8-Substituted Adenosine Derivatives as Dual Acting A(2A) and A(3) Adenosine Receptor Ligands

Truncated N(6)-substituted-4′-oxo- and 4′-thioadenosine derivatives with C2 or C8 substitution were studied as dual acting A(2A) and A(3) adenosine receptor (AR) ligands. The lithiation-mediated stannyl transfer and palladium-catalyzed cross coupling reactions were utilized for functionalization of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hou, Xiyan, Majik, Mahesh S., Kim, Kyunglim, Pyee, Yuna, Lee, Yoonji, Alexander, Varughese, Chung, Hwa-Jin, Lee, Hyuk Woo, Chandra, Girish, Lee, Jin Hee, Park, Seul-gi, Choi, Won Jun, Kim, Hea Ok, Phan, Khai, Gao, Zhan-Guo, Jacobson, Kenneth A., Choi, Sun, Lee, Sang Kook, Jeong, Lak Shin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266722/
https://ncbi.nlm.nih.gov/pubmed/22142423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201229j
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