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Identification of the Mhc Region as an Asthma Susceptibility Locus in Recombinant Congenic Mice

Mouse models of allergic asthma are characterized by airway hyperreactivity (AHR), Th2-driven eosinophilic airway inflammation, high allergen-specific IgE (anti-OVA IgE) levels in serum, and airway remodeling. Because asthma susceptibility has a strong genetic component, we aimed to identify new ast...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nawijn, Martijn C., Piavaux, Benoit J. A., Jeurink, Prescilla V., Gras, Renée, Reinders, Marjan A., Stearns, Timothy, Foote, Simon, Hylkema, Machteld N., Groot, Peter C., Korstanje, Ron, Oosterhout, Antoon J. M. Van
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266060/
https://ncbi.nlm.nih.gov/pubmed/20971879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0369OC
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