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TLR-2 Activation Induces Regulatory T Cells and Long-Term Suppression of Asthma Manifestations in Mice

Asthma is a chronic inflammatory disease of the airways characterized by variable airway obstruction and airway hyperresponsiveness (AHR). The T regulatory (Treg) cell subset is critically important for the regulation of immune responses. Adoptive transfer of Treg cells has been shown to be sufficie...

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Detalhes bibliográficos
Main Authors: Nawijn, Martijn C., Motta, Alexandre C., Gras, Renée, Shirinbak, Soheila, Maazi, Hadi, van Oosterhout, Antoon J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564817/
https://ncbi.nlm.nih.gov/pubmed/23393567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055307
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