Infection-dependent phenotypes in MHC-congenic mice are not due to MHC: can we trust congenic animals?

BACKGROUND: Congenic strains of mice are assumed to differ only at a single gene or region of the genome. These mice have great importance in evaluating the function of genes. However, their utility depends on the maintenance of this true congenic nature. Although, accumulating evidence suggests tha...

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Detalhes bibliográficos
Main Authors: McClelland, Erin E, Damjanovich, Kristy, Gardner, Kyle, Groesbeck, Zack J, Ma, Maggie S, Nibley, Megan, Richardson, Kelly S, Wilkinson, Maureen, Morrison, Linda C, Bernhardt, Paul, Potts, Wayne K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC481063/
https://ncbi.nlm.nih.gov/pubmed/15245582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-5-14
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