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Relationship of Virulence Factor Expression to Evolved Virulence in Mouse-Passaged Cryptococcus neoformans Lines

Serial passage of Cryptococcus neoformans in mice increases virulence relative to the nonpassaged line. Postpassaged lines showed no difference in the expression of most known virulence factors, with the exception that the more virulent lines had smaller capsules in vitro. These data imply that othe...

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Detalhes bibliográficos
Main Authors: McClelland, Erin E., Perrine, Wesley T., Potts, Wayne K., Casadevall, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230917/
https://ncbi.nlm.nih.gov/pubmed/16177390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.7047-7050.2005
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