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Relationship of Virulence Factor Expression to Evolved Virulence in Mouse-Passaged Cryptococcus neoformans Lines

Serial passage of Cryptococcus neoformans in mice increases virulence relative to the nonpassaged line. Postpassaged lines showed no difference in the expression of most known virulence factors, with the exception that the more virulent lines had smaller capsules in vitro. These data imply that othe...

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Autors principals: McClelland, Erin E., Perrine, Wesley T., Potts, Wayne K., Casadevall, Arturo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230917/
https://ncbi.nlm.nih.gov/pubmed/16177390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.7047-7050.2005
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