Mice That Are Congenic for the char2 Locus Are Susceptible to Malaria

A major advance has been made towards the positional cloning of char2 (a quantitative trait locus encoding resistance to Plasmodium chabaudi malaria). Mice congenic for the locus have been used to fine map the gene and to prove that char2 plays a significant role in the outcome of malarial infection...

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Bibliografiske detaljer
Main Authors: Burt, Rachel A., Marshall, Vikki M., Wagglen, Jamie, Rodda, Fleur R., Senyschen, Danielle, Baldwin, Tracey M., Buckingham, Lynn A., Foote, Simon J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC128146/
https://ncbi.nlm.nih.gov/pubmed/12117997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4750-4753.2002
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