Mice That Are Congenic for the char2 Locus Are Susceptible to Malaria

A major advance has been made towards the positional cloning of char2 (a quantitative trait locus encoding resistance to Plasmodium chabaudi malaria). Mice congenic for the locus have been used to fine map the gene and to prove that char2 plays a significant role in the outcome of malarial infection...

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Detalhes bibliográficos
Main Authors: Burt, Rachel A., Marshall, Vikki M., Wagglen, Jamie, Rodda, Fleur R., Senyschen, Danielle, Baldwin, Tracey M., Buckingham, Lynn A., Foote, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128146/
https://ncbi.nlm.nih.gov/pubmed/12117997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4750-4753.2002
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