Whole genome sequencing of matched primary and metastatic acral melanomas

Next generation sequencing has enabled systematic discovery of mutational spectra in cancer samples. Here, we used whole genome sequencing to characterize somatic mutations and structural variation in a primary acral melanoma and its lymph node metastasis. Our data show that the somatic mutational r...

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Main Authors: Turajlic, Samra, Furney, Simon J., Lambros, Maryou B., Mitsopoulos, Costas, Kozarewa, Iwanka, Geyer, Felipe C., MacKay, Alan, Hakas, Jarle, Zvelebil, Marketa, Lord, Christopher J., Ashworth, Alan, Thomas, Meirion, Stamp, Gordon, Larkin, James, Reis-Filho, Jorge S., Marais, Richard
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2012
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266028/
https://ncbi.nlm.nih.gov/pubmed/22183965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.125591.111
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