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Deriving a Mutation Index of Carcinogenicity Using Protein Structure and Protein Interfaces

With the advent of Next Generation Sequencing the identification of mutations in the genomes of healthy and diseased tissues has become commonplace. While much progress has been made to elucidate the aetiology of disease processes in cancer, the contributions to disease that many individual mutation...

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Main Authors: Espinosa, Octavio, Mitsopoulos, Konstantinos, Hakas, Jarle, Pearl, Frances, Zvelebil, Marketa
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893166/
https://ncbi.nlm.nih.gov/pubmed/24454733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084598
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