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Deriving a Mutation Index of Carcinogenicity Using Protein Structure and Protein Interfaces

With the advent of Next Generation Sequencing the identification of mutations in the genomes of healthy and diseased tissues has become commonplace. While much progress has been made to elucidate the aetiology of disease processes in cancer, the contributions to disease that many individual mutation...

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Main Authors: Espinosa, Octavio, Mitsopoulos, Konstantinos, Hakas, Jarle, Pearl, Frances, Zvelebil, Marketa
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893166/
https://ncbi.nlm.nih.gov/pubmed/24454733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084598
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