Whole genome sequencing of matched primary and metastatic acral melanomas

Next generation sequencing has enabled systematic discovery of mutational spectra in cancer samples. Here, we used whole genome sequencing to characterize somatic mutations and structural variation in a primary acral melanoma and its lymph node metastasis. Our data show that the somatic mutational r...

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Detalhes bibliográficos
Main Authors: Turajlic, Samra, Furney, Simon J., Lambros, Maryou B., Mitsopoulos, Costas, Kozarewa, Iwanka, Geyer, Felipe C., MacKay, Alan, Hakas, Jarle, Zvelebil, Marketa, Lord, Christopher J., Ashworth, Alan, Thomas, Meirion, Stamp, Gordon, Larkin, James, Reis-Filho, Jorge S., Marais, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266028/
https://ncbi.nlm.nih.gov/pubmed/22183965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.125591.111
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