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Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen
Therapies that target estrogen signaling have made a very considerable contribution to reducing mortality from breast cancer. However, resistance to tamoxifen remains a major clinical problem. Here we have used a genome-wide functional profiling approach to identify multiple genes that confer resist...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286962/ https://ncbi.nlm.nih.gov/pubmed/21482774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018872108 |
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