Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation

The p63 transcription factor (TP63) is critical in development, growth and differentiation of stratifying epithelia. This is highlighted by the severity of congenital abnormalities caused by TP63 mutations in humans, the dramatic phenotypes in knockout mice and de-regulation of TP63 expression in ne...

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Main Authors: McDade, Simon S., Henry, Alexandra E., Pivato, Geraldine P., Kozarewa, Iwanka, Mitsopoulos, Constantinos, Fenwick, Kerry, Assiotis, Ioannis, Hakas, Jarle, Zvelebil, Marketa, Orr, Nicholas, Lord, Christopher J., Patel, Daksha, Ashworth, Alan, McCance, Dennis J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Gene Regulation, Chromatin and Epigenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424553/
https://ncbi.nlm.nih.gov/pubmed/22573176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks389
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