Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation

The p63 transcription factor (TP63) is critical in development, growth and differentiation of stratifying epithelia. This is highlighted by the severity of congenital abnormalities caused by TP63 mutations in humans, the dramatic phenotypes in knockout mice and de-regulation of TP63 expression in ne...

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Bibliographic Details
Main Authors: McDade, Simon S., Henry, Alexandra E., Pivato, Geraldine P., Kozarewa, Iwanka, Mitsopoulos, Constantinos, Fenwick, Kerry, Assiotis, Ioannis, Hakas, Jarle, Zvelebil, Marketa, Orr, Nicholas, Lord, Christopher J., Patel, Daksha, Ashworth, Alan, McCance, Dennis J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Gene Regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424553/
https://ncbi.nlm.nih.gov/pubmed/22573176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks389
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