Whole genome sequencing of matched primary and metastatic acral melanomas

Next generation sequencing has enabled systematic discovery of mutational spectra in cancer samples. Here, we used whole genome sequencing to characterize somatic mutations and structural variation in a primary acral melanoma and its lymph node metastasis. Our data show that the somatic mutational r...

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Bibliografiske detaljer
Main Authors: Turajlic, Samra, Furney, Simon J., Lambros, Maryou B., Mitsopoulos, Costas, Kozarewa, Iwanka, Geyer, Felipe C., MacKay, Alan, Hakas, Jarle, Zvelebil, Marketa, Lord, Christopher J., Ashworth, Alan, Thomas, Meirion, Stamp, Gordon, Larkin, James, Reis-Filho, Jorge S., Marais, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266028/
https://ncbi.nlm.nih.gov/pubmed/22183965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.125591.111
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