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FAK and talin: Who is taking whom to the integrin engagement party?

In this issue, Lawson et al. provide new insight into the relationship between FAK and talin during assembly of integrin adhesions on fibronectin. They show that FAK is upstream of talin, and that talin is not required for FAK recruitment or for integrin activation at nascent adhesions. However, FAK...

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Detalles Bibliográficos
Main Authors: Serrels, Bryan, Frame, Margaret C.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265951/
https://ncbi.nlm.nih.gov/pubmed/22270914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201112128
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