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Rapid synthesis of long-chain deoxyribooligonucleotides by the N-methylimidazolide phosphotriester method.

A modified phosphotriester method has been employed for the efficient chemical synthesis of long-chain deoxyribooligonucleotides. During the course of this work, a general and rapid procedure was developed for the preparation of 24-62-mers in solution. Preparative reversed phase column chromatograph...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Efimov, V A, Buryakova, A A, Reverdatto, S V, Chakhmakhcheva, O G, Ovchinnikov YuA
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1983
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326588/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6324083/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.23.8369
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