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Rapid synthesis of long-chain deoxyribooligonucleotides by the N-methylimidazolide phosphotriester method.

A modified phosphotriester method has been employed for the efficient chemical synthesis of long-chain deoxyribooligonucleotides. During the course of this work, a general and rapid procedure was developed for the preparation of 24-62-mers in solution. Preparative reversed phase column chromatograph...

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Sonraí bibleagrafaíochta
Foilsithe in:Nucleic Acids Res
Príomhchruthaitheoirí: Efimov, V A, Buryakova, A A, Reverdatto, S V, Chakhmakhcheva, O G, Ovchinnikov YuA
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Oxford University Press 1983
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326588/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6324083/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.23.8369
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