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Rapid synthesis of long-chain deoxyribooligonucleotides by the N-methylimidazolide phosphotriester method.
A modified phosphotriester method has been employed for the efficient chemical synthesis of long-chain deoxyribooligonucleotides. During the course of this work, a general and rapid procedure was developed for the preparation of 24-62-mers in solution. Preparative reversed phase column chromatograph...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1983
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6324083/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.23.8369 |
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