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Glutamate carboxypeptidase II (GCPII) inhibitor displays anti-glutamate and anti-cocaine effects in an invertebrate assay

Glutamate carboxypeptidase II (GCPII) inhibitors are promising anti-glutamatergic and anti-addictive agents. We hypothesized that a GCPII inhibitor 2 (phosphonomethyl)pentanedioic acid (2-PMPA) would display anti-stereotypical activity in planarians. Experiments revealed that 2-PMPA displayed no ove...

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Main Authors: Tallarida, Chris, Song, Kevin, Raffa, Robert B., Rawls, Scott M.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265618/
https://ncbi.nlm.nih.gov/pubmed/21850438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-011-1052-6
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