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β-lactamase inhibitors display anti-seizure properties in an invertebrate assay
Antibiotics containing a β-lactam ring (e.g., ceftriaxone) display anti-glutamate effects that underlie their efficacy in animal models of CNS diseases (Rothstein et al., 2005). We hypothesized that the structurally related β-lactamase inhibitors (clavulanic acid, tazobactam)- which also contain a β...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924441/ https://ncbi.nlm.nih.gov/pubmed/20600649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.06.041 |
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