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A Novel Assay Platform for the Detection of Translation Modulators of Spermidine/Spermine Acetyltransferase

Spermidine/spermine-N1-acetyltransferase (SSAT) is a mitochondrial-localized enzyme that is highly inducible and tightly controlled and is the rate-limiting enzyme in polyamine catabolism. It is known that SSAT is induced when polyamine level increases. Although multiple mechanisms have been implica...

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Detalhes bibliográficos
Main Authors: Perez-Leal, Oscar, Abou-Gharbia, Magid, Gordon, John, Childers, Wayne E., Merali, Salim
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871977/
https://ncbi.nlm.nih.gov/pubmed/23701549
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