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Enhanced Bacteremia in Human Factor H Transgenic Rats Infected by Neisseria meningitidis
Neisseria meningitidis binds the complement downregulating protein, factor H (fH), which enables the organism to evade host defenses. Two fH ligands, fHbp and NspA, are known to bind specifically to human fH. We developed a human fH transgenic infant rat model to investigate the effect of human fH o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3264313/ https://ncbi.nlm.nih.gov/pubmed/22104107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05604-11 |
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