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Inhibition of the Alternative Pathway of Nonhuman Infant Complement by Porin B2 Contributes to Virulence of Neisseria meningitidis in the Infant Rat Model

Neisseria meningitidis utilizes capsular polysaccharide, lipooligosaccharide (LOS) sialic acid, factor H binding protein (fHbp), and neisserial surface protein A (NspA) to regulate the alternative pathway (AP) of complement. Using meningococcal mutants that lacked all four of the above-mentioned mol...

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Bibliografske podrobnosti
Main Authors: Lewis, Lisa A., Vu, David M., Granoff, Dan M., Ram, Sanjay
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019150/
https://ncbi.nlm.nih.gov/pubmed/24686052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01517-14
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