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Inhibition of the Alternative Pathway of Nonhuman Infant Complement by Porin B2 Contributes to Virulence of Neisseria meningitidis in the Infant Rat Model

Neisseria meningitidis utilizes capsular polysaccharide, lipooligosaccharide (LOS) sialic acid, factor H binding protein (fHbp), and neisserial surface protein A (NspA) to regulate the alternative pathway (AP) of complement. Using meningococcal mutants that lacked all four of the above-mentioned mol...

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Autori principali: Lewis, Lisa A., Vu, David M., Granoff, Dan M., Ram, Sanjay
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019150/
https://ncbi.nlm.nih.gov/pubmed/24686052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01517-14
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