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Resistance to Linezolid Caused by Modifications at Its Binding Site on the Ribosome
Linezolid is an oxazolidinone antibiotic in clinical use for the treatment of serious infections of resistant Gram-positive bacteria. It inhibits protein synthesis by binding to the peptidyl transferase center on the ribosome. Almost all known resistance mechanisms involve small alterations to the l...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3264260/ https://ncbi.nlm.nih.gov/pubmed/22143525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05702-11 |
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