Resistance to the Peptidyl Transferase Inhibitor Tiamulin Caused by Mutation of Ribosomal Protein L3

The antibiotic tiamulin targets the 50S subunit of the bacterial ribosome and interacts at the peptidyl transferase center. Tiamulin-resistant Escherichia coli mutants were isolated in order to elucidate mechanisms of resistance to the drug. No mutations in the rRNA were selected as resistance deter...

Полное описание

Библиографические подробности

Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	Bøsling, Jacob, Poulsen, Susan M., Vester, Birte, Long, Katherine S.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2003
Предметы:	Mechanisms of Resistance
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2892-2896.2003
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