Resistance to the Peptidyl Transferase Inhibitor Tiamulin Caused by Mutation of Ribosomal Protein L3

The antibiotic tiamulin targets the 50S subunit of the bacterial ribosome and interacts at the peptidyl transferase center. Tiamulin-resistant Escherichia coli mutants were isolated in order to elucidate mechanisms of resistance to the drug. No mutations in the rRNA were selected as resistance deter...

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מידע ביבליוגרפי

הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	Bøsling, Jacob, Poulsen, Susan M., Vester, Birte, Long, Katherine S.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2003
נושאים:	Mechanisms of Resistance
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2892-2896.2003
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