Resistance to the Peptidyl Transferase Inhibitor Tiamulin Caused by Mutation of Ribosomal Protein L3

The antibiotic tiamulin targets the 50S subunit of the bacterial ribosome and interacts at the peptidyl transferase center. Tiamulin-resistant Escherichia coli mutants were isolated in order to elucidate mechanisms of resistance to the drug. No mutations in the rRNA were selected as resistance deter...

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Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Bøsling, Jacob, Poulsen, Susan M., Vester, Birte, Long, Katherine S.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2003
Teme:	Mechanisms of Resistance
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2892-2896.2003
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