Resistance to the Peptidyl Transferase Inhibitor Tiamulin Caused by Mutation of Ribosomal Protein L3

The antibiotic tiamulin targets the 50S subunit of the bacterial ribosome and interacts at the peptidyl transferase center. Tiamulin-resistant Escherichia coli mutants were isolated in order to elucidate mechanisms of resistance to the drug. No mutations in the rRNA were selected as resistance deter...

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Dettagli Bibliografici

Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Bøsling, Jacob, Poulsen, Susan M., Vester, Birte, Long, Katherine S.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2892-2896.2003
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