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Synthesis of Biphenyl Proteomimetics as Estrogen Receptor-alpha Coactivator Binding Inhibitors
[Image: see text] A novel series of biphenyl proteomimetic compounds were designed as estrogen receptor-alpha (ERα) coactivator binding inhibitors. Synthesis was accomplished through a convergent approach, employing Suzuki coupling chemistry to ligate the individual modular units. Initial biological...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3263526/ https://ncbi.nlm.nih.gov/pubmed/19902964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol901999f |
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