VDAC1 selectively transfers apoptotic Ca(2+) signals to mitochondria

Voltage-dependent anion channels (VDACs) are expressed in three isoforms, with common channeling properties and different roles in cell survival. We show that VDAC1 silencing potentiates apoptotic challenges, whereas VDAC2 has the opposite effect. Although all three VDAC isoforms are equivalent in a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: De Stefani, D, Bononi, A, Romagnoli, A, Messina, A, De Pinto, V, Pinton, P, Rizzuto, R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263501/
https://ncbi.nlm.nih.gov/pubmed/21720385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.92
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker