VDAC1 selectively transfers apoptotic Ca(2+) signals to mitochondria

Voltage-dependent anion channels (VDACs) are expressed in three isoforms, with common channeling properties and different roles in cell survival. We show that VDAC1 silencing potentiates apoptotic challenges, whereas VDAC2 has the opposite effect. Although all three VDAC isoforms are equivalent in a...

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Detaylı Bibliyografya
Asıl Yazarlar: De Stefani, D, Bononi, A, Romagnoli, A, Messina, A, De Pinto, V, Pinton, P, Rizzuto, R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263501/
https://ncbi.nlm.nih.gov/pubmed/21720385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.92
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