Carregant...

Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function

In non-apoptotic cells, Bak constitutively resides in the mitochondrial outer membrane. In contrast, Bax is in a dynamic equilibrium between the cytosol and mitochondria, and is commonly predominant in the cytosol. In response to an apoptotic stimulus, Bax and Bak change conformation, leading to Bax...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Death Differ
Autors principals: Ma, S B, Nguyen, T N, Tan, I, Ninnis, R, Iyer, S, Stroud, D A, Menard, M, Kluck, R M, Ryan, M T, Dewson, G
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227151/
https://ncbi.nlm.nih.gov/pubmed/25146925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.119
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!