VDAC1 selectively transfers apoptotic Ca(2+) signals to mitochondria

Voltage-dependent anion channels (VDACs) are expressed in three isoforms, with common channeling properties and different roles in cell survival. We show that VDAC1 silencing potentiates apoptotic challenges, whereas VDAC2 has the opposite effect. Although all three VDAC isoforms are equivalent in a...

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Hlavní autoři: De Stefani, D, Bononi, A, Romagnoli, A, Messina, A, De Pinto, V, Pinton, P, Rizzuto, R
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263501/
https://ncbi.nlm.nih.gov/pubmed/21720385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.92
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